Protein Domain : DNA modification/repair radical SAM protein, putative IPR023874

Type  Family
Description  This entry represents a family of uncharacterised protein of about 400 amino acids in length that contains a radical SAM domain in the N-terminal half. Members of this family are present in about twenty percent of prokaryotic genomes, always paired with a member of the conserved hypothetical protein . Roughly forty percent of the members of that family exist as fusions with a uracil-DNA glycosylase-like region, . In DNA, uracil results from deamidation of cytosine, forming U/G mismatches that lead to mutation, and so uracil-DNA glycosylase is a DNA repair enzyme. This indirect connection, and the recurring role or radical SAM proteins in modification chemistries, suggest that this protein may act in DNA modification, repair, or both.
Short Name  DNA_rSAM_put

0 Child Features

0 Gene Families

0 Genes

0 Ontology Annotations

0 Parent Features

0 Publications

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