Protein Domain : Secreted and transmembrane protein 1 IPR033231

Type  Family
Description  Secreted and transmembrane protein 1 (SECTM1), also known as protein K-12, has been identified as a ligand for CD7, an immunoglobulin superfamily molecule with a role in T- and NK-cell activation and cytokine production [ ]. SECTM1 is a potent costimulatory ligand for T cell proliferation and is induced by IFN-gamma [, , ].The human genome contains only one SECTM gene, while the mouse genome contains two (SECTM1A and SECTM1B) [ ].
Short Name  SECTM1

0 Child Features

0 Gene Families

0 Genes

2 Ontology Annotations

0 Parent Features

0 Publications

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