v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | This entry represents the VPRBP/DCAF1 family, whose members include protein VPRBP from mammals [ ], protein mahjong form fruit flies [] and DCAF1 from worms and plants []. They are the substrate recognition component of the E3 ubiquitin-protein ligase complex. Human VPRBP is part of the CUL4A-RBX1-DDB1-DCAF1/VPRBP complex that mediates ubiquitination and proteasome-dependent degradation of proteins [ ]. VPRBP also has kinase activity and is capable of phosphorylating histone H2A on threonine 120 (H2AT120p) in a nucleosomal context []. |
| Short Name | VPRBP/DCAF1 |