Protein Domain : Neuromodulin, phosphorylation site IPR033137

Type	PTM
Description	Neuromodulin (also known as GAP-43, pp46, B-50, F1, and P-57) [ ] is an axonalmembrane protein associated with nerve growth. It is a major component of the motile growth cones that form the tips of elongating axons. Neuromodulin is anhydrophilic protein of 210 to 240 amino acid residues, which binds calmodulin and inhibits phosphatidylinositol phosphate kinase (PIP kinase). It isphosphorylated by protein kinase C, and regulates the binding of GTP to G(0) []. Neuromodulin contains an IQ motif.This entry represents a conserved region containing a serine residue which can be phosphorylated by protein kinase C [ ] and which is adjacent to the calmodulin-binding domain.
Short Name	Neuromodulin_P_site