Protein Domain : PH domain containing protein Boi1/Boi2-like IPR045188

Type  Family
Description  This entry represents a group of PH domain containing proteins, including Boi1/2 from budding yeasts and PKHJ1/Sesquipedalian1-2/PKHA3 from humans. Budding yeast Boi1/2 are involved in polar growth and required for fusion of secretory vesicles with plasma membrane at sites of polarised growth [ ]. Sesquipedalian-1/2 are inositol polyphosphate phosphatase interacting proteins required for receptor recycling from endosomes, both to the trans-Golgi network and to the plasma membrane []. PKHA3 plays a role in regulation of vesicular cargo transport from the trans-Golgi network to the plasma membrane []. It regulates Golgi phosphatidylinositol 4-phosphate (PtdIns4P) levels and activates the PtdIns4P phosphatase activity of SACM1L when it binds PtdIns4P in 'trans' configuration [].
Short Name  Boi1/Boi2-like

0 Child Features

0 Gene Families

0 Genes

0 Ontology Annotations

0 Parent Features

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