Protein Domain : Synembryn IPR008376

Type	Domain
Description	Synembryns are proteins that positively regulate synaptic transmission. Theyare actively required to maintain proper activity of the Go to Gq G-protein signalling network, which regulates neurotransmitter secretion in Caenorhabditis elegansby controlling the production and consumption of diacylglycerol [ ]. Inaddition to its role in the adult nervous system, synembryn is required to regulate a subset of centrosome movements in the early C. elegans embryo [].The protein appears to be concentrated in the cytoplasm of neurons. However,unlike other protein components of the Go-Gq signalling network, synembryn appears to be more concentrated in the cell soma than in axonal processesthroughout the nervous system [ ]. C. elegans synembryn reduction of functionmutants exhibit partial embryonic lethality [ ].
Short Name	Synembryn