Protein Domain : FRAS1-related extracellular matrix protein, N-terminal domain IPR045658

Type  Domain
Description  This entry represents a domain found at the N terminus of FRAS1-related extracellular matrix proteins (also known as Frem related proteins) predominantly in chordates. In humans, the FRAS1-related extracellular matrix protein 1 was reported to be essential for the normal adhesion of the embryonic epidermis [ ]. FRAS1-related extracellular matrix protein 2 is involved in the development of eyelids and the anterior segment of the eyeballs and has been related to cryptophthalmos (a rare congenital disorder characterized by ocular dysplasia with eyelid malformation) [, ].
Short Name  FRAS1-rel_N
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