Protein Domain : Neuromodulin, palmitoylation site IPR018243

Type  PTM
Description  Neuromodulin (also known as GAP-43, pp46, B-50, F1, and P-57) [ ] is an axonalmembrane protein associated with nerve growth. It is a major component of the motile growth cones that form the tips of elongating axons. Neuromodulin is anhydrophilic protein of 210 to 240 amino acid residues, which binds calmodulin and inhibits phosphatidylinositol phosphate kinase (PIP kinase). It isphosphorylated by protein kinase C, and regulates the binding of GTP to G(0) []. Neuromodulin contains an IQ motif.This entry represents the N-terminal extremity containing two cysteine residues which are palmitoylated and are responsible for the attachment of the protein to the membrane.
Short Name  Neuromodulin_palmitoyl_site

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