Protein Domain : FREE1 IPR045893

Type  Family
Description  FYVE domain protein required for endosomal sorting 1 (FREE1), also known as FYVE domain-containing protein 1 (FYVE1) is a component of the endosomal sorting complex required for transport (ESCRT), involved in multivesicular body (MVB) protein sorting and plant growth [ , , ]. It negatively regulates salt stress tolerance via a negative feedback loop involving abscisic acid (ABA) signaling pathway []. The the N-terminal domain of FREE1 is required for the interaction with the Ubiquitin-binding ESCRT-I subunit proteins VPS23A and B, the FYVE domain is required for phosphatidylinositol-3-phosphate (PI3P) binding, and the C-terminal domain for the binding to ubiquitin [ , ].
Short Name  FREE1

0 Child Features

0 Gene Families

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2 Ontology Annotations

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