Protein Domain : Acetyl-CoA carboxylase carboxyl transferase, beta subunit IPR000438

Type  Family
Description  Fatty acid synthesis involves a set of reactions, starting with carboxylation of acetyl-CoA to malonyl-CoA. This is an irreversible reaction, catalysed by the acetyl-CoA carboxylase complex ( ); a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and two non-identical carboxyl transferase subunits (alpha and beta) in a 2:2 association [ ]. The reaction involves two steps: Biotin carrier protein + ATP + HCO 3-= Carboxybiotin carrier protein + ADP + P iCarboxybiotin carrier protein + Acetyl-CoA = Malonyl-CoA + Biotin carrier proteinIn the first step, biotin carboxylase catalyses the carboxylation of the carrier protein to form an intermediate. Next, the transcarboxylase complex transfers the carboxyl group from the intermediate to acetyl-CoA forming malonyl-CoA.
Short Name  Acetyl_CoA_COase_Trfase_b_su

0 Child Features

1 Gene Families

12 Genes

3 Ontology Annotations

0 Parent Features

3 Publications

USDA
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