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Search results 16101 to 16200 out of 30763 for seed protein

Category restricted to ProteinDomain (x)

0.034s

Categories

Category: ProteinDomain
Type Details Score
Protein Domain
Name: CppA, N-terminal
Type: Domain
Description: This is the N-terminal domain of the CppA protein found mainly in species of Streptococcus. CppA is a putative C3-glycoprotein degrading proteinase, involved in pathogenicity [ , ].
Protein Domain
Name: Domain of unknown function DUF2062
Type: Domain
Description: This domain, found in various prokaryotic proteins, has no known function. It is found at the C-terminal of family 2 glycosyltransferase proteins, in addition to proteins of unknown function.
Protein Domain
Name: Phage tail tube protein-like
Type: Family
Description: This family of proteins are tube proteins which polymerise to form the phage tails. The characteristics of the protein distribution suggest prophage matches in addition to the phage matches.
Protein Domain
Name: KNL2-like
Type: Family
Description: This entry includes Caenorhabditis elegans Knl2 (kinetochore null protein 2) and related proteins. Knl2 is a Myb DNA-binding domain-containing protein required for CENP-A loading and kinetochore assembly [ ].
Protein Domain
Name: FAD-dependent oxidoreductase 2, FAD binding domain
Type: Domain
Description: This domain is found in proteins that bind FAD, mainly in FAD-dependent oxidoreductase family 2 proteins, such as the flavoprotein subunits from succinate and fumarate dehydrogenase, and aspartate oxidase [].
Protein Domain
Name: PucC-related
Type: Family
Description: The PucC protein is required for high-level transcription of the PUC operon. It is an integral membrane protein. The entry includes PucC and other proteins from the Major Facilitator Superfamily.
Protein Domain
Name: Fatty acid synthase alpha subunit, yeast
Type: Family
Description: Fatty acid synthetase catalyses the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The alpha subunit contains domains for: acyl carrier protein, 3-oxoacyl-[acyl-carrier-protein] reductase, and 3-oxoacyl-[acyl-carrier-protein]synthase [ ].
Protein Domain
Name: Glycosyl hydrolase family 99
Type: Family
Description: This family contains endomannosidases and endomannosidase-like proteins. Glycoprotein endo-alpha-1,2-mannosidase hydrolyses the terminal alpha-D-glucosyl-(1,3)-D-mannosyl unit from the GlcMan9(GlcNAc)2 oligosaccharide component of the glycoprotein produced in the Golgi membrane [ , ].
Protein Domain
Name: NolW-like superfamily
Type: Homologous_superfamily
Description: This is a group of NolW-like proteins, which are closely related to bacterial type II and III secretion system protein ( ). NolW proteins have putative membrane-spanning regions [ ].
Protein Domain
Name: ThiS, thiamine-biosynthesis
Type: Family
Description: This entry identifies the ThiS family, which are thiamine-biosynthesis proteins related to MoaD. MoaD is a molybdenum cofactor biosynthesis protein. Both ThiS and MoaD proteins are involved in sulphur transfer.
Protein Domain
Name: Dicarboxylate carrier MatC N-terminal
Type: Domain
Description: This entry represents the N-terminal region of the bacterial dicarboxylate carrier protein MatC. The MatC protein is an integral membrane protein that could function as a malonate carrier [ ].
Protein Domain
Name: NolW-like
Type: Domain
Description: This is a group of NolW-like proteins, which are closely related to bacterial type II and III secretion system protein ( ). NolW proteins have putative membrane-spanning regions [ ].
Protein Domain
Name: Putative lipoprotein, bacteria
Type: Family
Description: All the proteins in this family have a N-terminal lipoprotein attachment motif. No member of this family has been functionally characterized. Proteins in this family are found in Firmicute bacteria.
Protein Domain
Name: Biofilm regulator BssS
Type: Family
Description: The BssS protein family is a group of proteins that are involved in regulation of biofilm formation [ ]. Proteins in this family are approximately 80 amino acids in length.
Protein Domain
Name: Regulator of G-protein signalling Egl-10, RGS domain
Type: Domain
Description: Egl-10 regulates G protein signalling in the C. elegans nervous system. It is related to regulator of G protein signaling R7 subfamily of proteins, orthologue of human RGS7 [ ].
Protein Domain
Name: NACHT, LRR and PYD domains-containing protein, helical domain HD2
Type: Domain
Description: This entry represents the second of two helical domains (HD2) found in the NLRC proteins [ ], the NOD2 protein [] and NACHT, LRR and PYD domains-containing proteins [, ].
Protein Domain
Name: UPF0767 family
Type: Family
Description: This family of uncharacterised proteins is found in eukaryotes. Proteins in this family are described as small integral membrane protein 12. There are two conserved sequence motifs: IGYN and SPSL.
Protein Domain
Name: Serine-protein kinase, PrkA
Type: Family
Description: PrkA proteins are bacterial and archaeal serine kinases approximately 630 residues in length. They possesses the A-motif of nucleotide-binding proteins and exhibit distant homology to eukaryotic protein kinases [ ].
Protein Domain
Name: RESP18 domain
Type: Domain
Description: This domain is found in the glucocorticoid-responsive protein regulated endocrine-specific protein 18 (RESP18) and in the N-terminal extracellular region of receptor-type tyrosine-protein phosphatases IA-2 (RPTPN) and RPTPN2 [ , ].
Protein Domain
Name: Glucocorticoid-induced transcript 1/FAM117
Type: Family
Description: This family includes glucocorticoid-induced transcript 1 protein, a protein of unkown function that is expressed at specific stages of T-cell and sperm maturation [ ], and uncharacterised proteins FAM117A and FAM117B.
Protein Domain
Name: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain
Type: Domain
Description: This domain is found in many different proteins including mannosyl-glycoprotein endo-beta-N-acetylglucosamidase ( ). It is also found in flagellar protein J ( ), which has been shown to hydrolyse peptidoglycan [].
Protein Domain
Name: Gp120 core superfamily
Type: Homologous_superfamily
Description: The envelope glycoprotein Gp160 of HIV1 and Simian immunodeficiency virus (SIV) is cleaved into the surface protein Gp120 and the transmembrane protein Gp41. This superfamily represents the Gp120 core [ ].
Protein Domain
Name: Yae1-like
Type: Family
Description: This entry includes yeast Yae-1, human YAE1D1 (Yae1 domain-containing protein 1) and related proteins from eukaryotes. Yae1 depletion results in defective Fe-S maturation of the ribosome-associated ABC protein Rli1 [ ].
Protein Domain
Name: Chordopoxvirus G2
Type: Family
Description: This family consists of several Chordopoxvirus isatin-beta-thiosemicarbazone dependent protein (protein G2) sequences. Inactivation of the gene coding for this protein renders the virus dependent upon isatin-beta-thiosemicarbazone (IBT) for growth [ ].
Protein Domain
Name: Domain of unknown function DUF6484
Type: Domain
Description: This domain of unknown function is found in uncharacterised proteins mostly from Proteobacteria. Many proteins containing this domain are related to the Type VI secretion system and to Phage-related baseplate proteins.
Protein Domain
Name: Envelope glycoprotein, lentivirus
Type: Family
Description: The proteins in this family are envelope glycoproteins from feline immunodeficiency retrovirus. The process of lentiviral envelope glycoprotein-mediated fusion of membranes is essential for viral entry and syncytia formation [ ].
Protein Domain
Name: Leucyl/phenylalanyl-tRNA-protein transferase
Type: Family
Description: Leucyl/phenylalanyl-tRNA--protein transferase transfers a Leu or Phe to the amino end of certain proteins to enable degradation. The N-terminal residue controls the biological half-life of many proteins via the N-end rule pathway.
Protein Domain
Name: XkdM-like superfamily
Type: Homologous_superfamily
Description: This is a superfamily of phage tail tube proteins including protein XkdM from phage-like element PBSX protein ( ) whose structure adopts a beta barrel flanked with alpha helical regions [ ].
Protein Domain
Name: Hepadnaviral P protein, N-terminal
Type: Domain
Description: This domain is at the N terminus of hepadnavirus P proteins and covers the so-called terminal protein and the spacer region of the protein. This domain is always associated with and .
Protein Domain
Name: MAFF2-related
Type: Family
Description: This family of short membrane proteins are related to the protein Maff2. Maff2 lies just outside the direct repeats of a tetracycline resistance transposable element. This protein family may contain transmembrane helices.
Protein Domain
Name: RecQ mediated genome instability protein, N-terminal OB-fold superfamily
Type: Homologous_superfamily
Description: This entry represents the N-terminal OB-fold domain of RMI (RecQ-mediated genome instability protein) proteins [ ]. This domain forms a stable complex with Bloom syndrome protein BLM and DNA topoisomerase 3-alpha [].
Protein Domain
Name: GBS Bsp-like
Type: Repeat
Description: This repeat is found in a number of Streptococcus proteins including some hypothetical proteins and Bsp. Bsp is a protein of group B Streptococcus (GBS) which might control cell morphology [ ].
Protein Domain
Name: Leucine-rich repeat-containing 41
Type: Family
Description: Leucine-rich repeat-containing 41 protein is probably a substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins [ ].
Protein Domain
Name: [FeFe]-hydrogenase maturation HydE, radical SAM
Type: Family
Description: This entry describes the radical SAM protein HydE, one of a pair of radical SAM proteins, along with GTP-binding protein HydF, for maturation of [FeFe]-hydrogenase in Chlamydomonas reinhardtii and numerous bacteria [, ].
Protein Domain
Name: Enolase-like, C-terminal domain superfamily
Type: Homologous_superfamily
Description: The C-terminal domain of the enolase adopts a TIM barrel fold that contains a metal binding site [ ]. Proteins containing this domain also include D-glucarate dehydratase-like proteins and some uncharacterised proteins [].
Protein Domain
Name: Transmembrane secretion effector
Type: Family
Description: This is a family of transport proteins. Members of this family include a protein responsible for the secretion of the ferric chelator, enterobactin [ ], and a protein involved in antibiotic resistance [].
Protein Domain
Name: Conjugative transposon, TraN
Type: Family
Description: This entry represents the TraN protein, which is encoded by transfer region genes of conjugative transposons of Bacteroides. This protein is related to conjugative transfer proteins VirB9 and TrbG of Agrobacterium Ti plasmids.
Protein Domain
Name: Pkip-1
Type: Family
Description: Pkip-1 is a baculoviral gene encoding a protein kinase-interacting protein. It interacts with and stimulates the activity of virus-encoded protein kinase PK-1 [ , ]. Pkip-1 is not essential for virus replication [].
Protein Domain
Name: Domain of unknown function DUF5105
Type: Domain
Description: This entry represents a domain found in a group of uncharacterised bacterial proteins. Its function is not known. Proteins containing this domain include a putative lipoprotein, ycdA, whose structure has been revealed (PDB:4r4g).
Protein Domain
Name: Guanine nucleotide-binding protein-like 3, N-terminal domain
Type: Domain
Description: This entry represents an N-terminal domain found in Guanine nucleotide-binding protein-like 3 [ , ], Nuclear GTP-binding protein NUG1 [], GTPase Grn1 [] and other related proteins. The function of this domain is unknown.
Protein Domain
Name: Adenovirus E3
Type: Family
Description: This family consists of several Adenovirus E3 proteins. The E3 protein does not seem to be essential for virus replication in cultured cells suggesting that the protein may function in virus-host interactions [ ].
Protein Domain
Name: Mycoplasma-specific lipoprotein, type 3
Type: Family
Description: This family of lipoproteins is Mycoplasma specific, and includes a variety of hypothetical proteins [ ]. They all have a prokaryotic membrane lipoprotein lipid attachment site which is probable acts as a membrane anchor.
Protein Domain
Name: Lysine methyltransferase
Type: Family
Description: This entry represents a group of lysine methyltransferases. Characterised members of this family are protein methyltransferases targetting Lys residues in specific proteins, including calmodulin, VCP, Kin17 and Hsp70 proteins [ , , , ].
Protein Domain
Name: Class III signal peptide protein, archaeosortase D/PIP-CTERM system
Type: Family
Description: Members of this protein family are short proteins that consist largely of the archaeal class III signal peptide. Members are encoded in a gene cassette between archaeosortase D and its PIP-CTERM target protein [ ].
Protein Domain
Name: YmaF
Type: Family
Description: This family of proteins contain 6 HXH motifs and is named after the B. subtilis YmaF protein. The function of these proteins is unknown but it seems likely that they are involved in metal binding.
Protein Domain
Name: Cupin fold metalloprotein WbuC, N-terminal domain
Type: Domain
Description: This presumed domain is found at the N terminus of WbuC family member Cupin fold metalloprotein and similar proteins found mainly in Proteobacteria and Bacteroidetes. These proteins contain 1 or 2 copies of the domain.
Protein Domain
Name: Bacterial shufflon protein, N-terminal
Type: Domain
Description: This domain represents the high-similarity N-terminal constant region shared by shufflon proteins. Shufflon proteins are created as a result of a clustered inversion region. The proteins retain a constant N-terminal domain, with different C-terminal domains.
Protein Domain
Name: Transcription regulator PadR, acidobacterial-type
Type: Family
Description: Proteins in this entry are putative transcriptional regulators of the wider PadR family, and are found primarily in species of the acidobacteria. These proteins are regularly encoded in the vicinity of a putative transporter protein
Protein Domain
Name: A-alpha-Y mating type-dependent binding domain
Type: Domain
Description: Mating-type protein A-alpha specifies the A-alpha-Y mating type. The A-alpha-Y protein binds to the AalphaZ protein of another mating type in Schizophyllum commune [ ] and may also regulate gene expression of the homokaryotic cell.
Protein Domain
Name: Hemolectin/hemocytin
Type: Family
Description: This group represents arthropod hemolectin/hemocytin, which are proteins with structural similarity to the human von Willebrand factor [ ], each containing a single proteinase inhibitor domain homologue related to MEROPS proteinase inhibitor family I8 (clan IA).
Protein Domain
Name: S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea
Type: Family
Description: Members of this protein family are the archaeal protein TYW1 [ ], a radical SAM protein that catalyzes the second step in creating the wye-bases, wyosine and derivatives such as wybutosine, for tRNA base modification [].
Protein Domain
Name: Herpesvirus UL37, HHV-5-related
Type: Family
Description: This family consists of several Betaherpesvirus immediate-early glycoprotein UL37 sequences. The human cytomegalovirus (HCMV) UL37 immediate-early regulatory protein is a type I integral membrane N-glycoprotein which traffics through the ER and the Golgi network [ ].
Protein Domain
Name: Cell morphogenesis central region
Type: Domain
Description: This entry represents the central region of proteins that are involved in cell morphogenesis. Among these are furry proteins from flies [ , ], proteins PAG1 from budding yeasts [] and Mor2 from fission yeasts [].
Protein Domain
Name: Small EDRK-rich factor 1/2
Type: Family
Description: This entry includes SERF1, SERF2 and related proteins. They are short proteins rich in aspartate, glutamate, lysine and arginine. Although the function of these proteins is unknown, they are found to be ubiquitously expressed [ ].
Protein Domain
Name: Borrelia plasmid, OrfA
Type: Family
Description: The proteins in this entry are encoded by an open reading frame in plasmid borne DNA repeats of Borrelia species. This protein is known as ORF-A [ ]. The function of this putative protein is unknown.
Protein Domain
Name: PqqD family protein, HPr-rel-A system
Type: Family
Description: Members of this protein show distant homology to PqqD, and belong to a three-gene cassette that included the HPr kinase related protein family of . The role of the cassette, and of this protein, are unknown.
Protein Domain
Name: Domain of unknown function DUF6535
Type: Domain
Description: This entry represents an integral membrane region of a large family of fungal proteins. This region likely contains three transmembrane helices. Some proteins contain two copies of this region. The function of these proteins is unknown.
Protein Domain
Name: Ebola nucleoprotein
Type: Family
Description: This family consists of Ebola virus sp., Lake Victoria marburgvirus nucleoproteins. These proteins are responsible for encapsidation of genomic RNA. It has been found that nucleoprotein DNA vaccines can offer protection from the virus [ ].
Protein Domain
Name: E3 ubiquitin ligase BIG BROTHER-like
Type: Family
Description: This entry represents a group of plant proteins, including AtBBR (At3g19910) from Arabidopsis. Their function is not clear. They share protein sequence similarity with E3 ubiquitin-protein ligase BIG BROTHER in their RING finger domain [ ].
Protein Domain
Name: Phosphodiester glycosidase
Type: Domain
Description: This domain can be found in many bacterial and several viral proteins and can be identified in the mammalian transmembrane glycoprotein N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA). Some proteins containing this domain may function as phosphodiester glycosidases [ ].
Protein Domain
Name: Rad52 family
Type: Family
Description: The DNA single-strand annealing proteins (SSAPs), such as RecT, Red-beta, ERF and Rad52, function in RecA-dependent and RecA-independent DNA recombination pathways. This family includes proteins related to Rad52. These proteins contain two helix-hairpin-helix motifs [ ].
Protein Domain
Name: Mitochondria-eating protein, C-terminal domain
Type: Domain
Description: This domain is found at the C terminus of mitochondria-eating proteins. Proteins containing this domain regulate mitochondrial quality. They have a role in damaged mitochondrial protein degradation and in damaged mitochondria degradation [ , , ].
Protein Domain
Name: Myb/SANT-like DNA-binding domain 4
Type: Domain
Description: This presumed domain appears to be related to other Myb/SANT-like DNA binding domains. In particular seems most related. Proteins containing this domain are greatly expanded in plants and appears in several proteins annotated as transposon proteins.
Protein Domain
Name: GTPase HflX, N-terminal
Type: Domain
Description: This domain represents the N-terminal region of GTP-binding HflX-like proteins [ , ]. These proteins interact with the 50S ribosome and are GTPases, hydrolysing GTP/GDP/ATP/ADP []. The N-terminal region is necessary for stability of the whole protein.
Protein Domain
Name: PAM68-like
Type: Family
Description: This entry includes chloroplastic protein PAM68 and some uncharacterised proteins from Cyanobacteria (blue-green algae). PAM68 is involved in early steps in photosystem II (PSII) biogenesis and in maturation and stability of newly synthesized psbA protein [ ].
Protein Domain
Name: RPA-interacting protein, central domain
Type: Domain
Description: This entry represents the middle domain of replication protein A (RPA) interacting protein. RPA interacting protein is involved in the import of RPA into the nucleus. This domain is responsible for interaction with RPA [ , ].
Protein Domain
Name: Rtr1/RPAP2 domain
Type: Domain
Description: This entry represents a domain found in RPAP2 (RNAP II associated polypeptide) protein and the yeast Rtr1 proteins. It has been suggested that this family of proteins are regulators of core RNA polymerase II function [ ].
Protein Domain
Name: CEP76, C2 domain
Type: Domain
Description: A C2 domain is usually involved in targeting proteins to cell membranes. This entry represents a C2 domain found in the CEP76 proteins [ ]. CEP76 is a centrosomal protein involved in regulation of centriole duplication [].
Protein Domain
Name: Axin beta-catenin binding
Type: Domain
Description: Proteins in this entry are found on the scaffolding protein Axin which is a component of the beta-catenin destruction complex. It competes with the tumour suppressor adenomatous polyposis coli protein (APC) for binding to beta-catenin [ ].
Protein Domain
Name: Histone lysine methyltransferase SET associated
Type: Domain
Description: The SET domain is a protein-protein interaction domain found in protein lysine methyltransferase enzymes. This entry represents a domain of unknown function which is associated with the SET domain and found in histone lysine methyltransferases [ ].
Protein Domain
Name: Putative nuclear localisation signal
Type: Domain
Description: NINJA proteins are novel interactor of JAZ proteins found in plants. NINJA proteins act as transcriptional repressors, the activity of which is mediated by a functional TPL-binding EAR repression motif upstream from this domain [ , ].
Protein Domain
Name: Ethanolamine utilization protein, PduT-related
Type: Family
Description: Genes encoding these proteins are found within ethanolamine utilization operons, in which a proteinaceous coat organelle is also encoded. They are closely related to the PduT protein encoded within propane-diol utilisation operons, which have the same structure.
Protein Domain
Name: YnbE-like lipoprotein
Type: Family
Description: This family includes E. coli YnbE ( ) and similar lipoproteins. Protein in this family are typically 60 amino acids in length and contain an N-terminal lipid attachment site. The specific function of these proteins is unknown.
Protein Domain
Name: Herpesvirus Glycoprotein B, PH-like domain 1
Type: Domain
Description: This entry represents first PH-like fold domain found in Herpesvirus glycoprotein B.Glycoprotein B is an envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells [ , ].
Protein Domain
Name: Sorbitol phosphotransferase enzyme II, C-terminal
Type: Domain
Description: The Gut family consists only of glucitol-specific permeases, but these occur both in Gram-negative and Gram-positive bacteria. Escherichia coli contains IIA protein, IIC protein and IIBC protein.This entry represents the C-terminal conserved region of the IIBC component.
Protein Domain
Name: Metalloproteinase lipoprotein, BF0631
Type: Family
Description: Members of this protein family are predicted to be zinc-dependent metalloproteinases, related to ulilysin and other members of the pappalysin family. They are found in the genera Bacteriodes and Prevotella. They are predicted to occur as lipoproteins.
Protein Domain
Name: FeoB, cytosolic helical domain
Type: Domain
Description: FeoB is a G-protein coupled membrane protein essential for Fe(II) uptake in prokaryotes. In the structures, a canonical G-protein domain (G domain) is followed by a helical bundle domain (S-domain) which is represented by this entry [].
Protein Domain
Name: Enolase C-terminal domain-like
Type: Domain
Description: This entry represents the C-terminal domain of the enolase, which adopts a TIM barrel fold that contains a metal binding site [ ]. Proteins containing this domain also include D-glucarate dehydratase-like proteins and some uncharacterised proteins [].
Protein Domain
Name: Glycine cleavage T-protein/YgfZ, C-terminal
Type: Homologous_superfamily
Description: This superfamily represents a β-barrel domain found at the C-terminal of the glycine cleavage T-protein (aminomethyltransferase) [ ] and in tRNA-modifying protein YgfZ. YgfZ binds folate and is likely to be a folate-dependent regulatory protein [, ].
Protein Domain
Name: RecB family nuclease, TM0106, putative
Type: Family
Description: Members of this uncharacterised protein family are found broadly but sporadically among bacteria. The N-terminal region is homologous to the Cas4 protein of CRISPR systems, although this protein family shows no signs of association with CRISPR repeats.
Protein Domain
Name: Vesicle transport v-SNARE, N-terminal
Type: Domain
Description: v-SNARE proteins are required for protein traffic between eukaryotic organelles. The v-SNAREs on transport vesicles interact with t-SNAREs on target membranes in order to facilitate this [ ]. This domain is the N-terminal half of the v-Snare proteins.
Protein Domain
Name: Pre-mRNA-splicing factor 19
Type: Domain
Description: This region is found specifically in PRP19-like protein. The region represented by this protein covers the sequence implicated in self-interaction and a coiled-coiled motif [ ]. PRP19-like proteins form an oligomer that is necessary for spliceosome assembly [].
Protein Domain
Name: Vesicle transport v-SNARE, N-terminal domain superfamily
Type: Homologous_superfamily
Description: v-SNARE proteins are required for protein traffic between eukaryotic organelles. The v-SNAREs on transport vesicles interact with t-SNAREs on target membranes in order to facilitate this [ ]. This domain is the N-terminal half of the v-Snare proteins.
Protein Domain
Name: Herpesvirus Glycoprotein B, PH-like domain 2 superfamily
Type: Homologous_superfamily
Description: This entry represents the second PH-like fold domain found in Herpesvirus glycoprotein B.Glycoprotein B is an envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells [ , ].
Protein Domain
Name: TM1070-like superfamily
Type: Homologous_superfamily
Description: This superfamily consists of several hypothetical bacterial proteins of around 125 resides in length, including the hypothetical protein TM1070 from Thermotoga maritima, which has a β-sandwich structure with a jelly-roll fold. The function of these proteins is unknown.
Protein Domain
Name: Tet-like 2OG-Fe(II) oxygenase
Type: Domain
Description: This entry represents an uncharacterised family of fungal proteins. The AlphaFold prediction for an example protein shows that it is most closely related to Tet-like dioxygenases. This strongly suggests that this family of proteins are DNA modification enzymes.
Protein Domain
Name: Facilitor Of iron transport 1/2
Type: Family
Description: Budding yeast Fit proteins (facilitor of iron transport) found on cell wall are mannoproteins implicated in the siderophore-iron bound transport. The Fit1-3 cell wall mannoproteins are attached to the beta-glucan layer through a GPI (glycosylphosphatidylinoisitol) anchor [ ].
Protein Domain
Name: Herpesvirus Glycoprotein B, PH-like domain 2
Type: Domain
Description: This entry represents the second PH-like fold domain found in Herpesvirus glycoprotein B.Glycoprotein B is an envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells [ , ].
Protein Domain
Name: Notch ligand, N-terminal domain
Type: Domain
Description: This entry represents a region of conserved sequence at the N terminus of several Notch ligand proteins, including Delta-like protein 1 (DLL1), 4 (DLL4) and Protein jagged-1. It plays a role in lipid binding [ , , ].
Protein Domain
Name: HnRNP R/Q splicing factor
Type: Family
Description: Sequences in this subfamily include the human heterogeneous nuclear ribonucleoproteins (hnRNP) R [ ], Q [] and APOBEC-1 complementation factor (aka APOBEC-1 stimulating protein) []. These proteins contain three RNA recognition domains and a somewhat variable C-terminal domain.
Protein Domain
Name: Gtt2-like, N-terminal
Type: Domain
Description: This entry represents the N-terminal GST-like TRX-fold domain found in the budding yeast Gtt2 protein. Gtt2 is a glutathione S-transferase involved in the glutaredoxin-mediated antioxidant activity [ ]. Proteins containing this domain also include some bacterial GST-like proteins.
Protein Domain
Name: Bacteriophage HP1, Orf24
Type: Family
Description: This entry represents proteins with unknown function found in tailed bacteriophages and Proteobacteria, including Putative tail tube protein from Haemophilus phage HP1 (Orf24). The characteristics of the protein distribution suggest prophage matches in addition to the phage matches.
Protein Domain
Name: BAT2, N-terminal
Type: Domain
Description: This entry represents the N terminus (approximately 200 residues) of the proline-rich protein BAT2 (also known as PRRC2A). BAT2 is similar to other proteins with large proline-rich domains, such as some nuclear proteins, collagens, elastin, and synapsin [ ].
Protein Domain
Name: SDA1, C-terminal domain
Type: Domain
Description: This domain is found in several SDA1 protein homologues. SDA1 is a Saccharomyces cerevisiae protein which is involved in the control of the actin cytoskeleton. The protein is essential for cell viability and is localised in the nucleus[ ].
Protein Domain
Name: UBL3-like, ubiquitin domain
Type: Domain
Description: This entry represents the ubiquitin domain found in ubiquitin-like protein 3 (UBL3) [ ] and related proteins, such as MUB1-6 from Arabidopsis []. The AtMUB proteins localize a specific subset of ubiquitin-conjugating (E2) enzymes to the plasma membrane [].
Protein Domain
Name: Helix-turn-helix protein, archaea
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found in archaea; they are typically between 161 and 201 amino acids in length. This family shares similarity with , suggesting it is a transcriptional regulatory protein.
Protein Domain
Name: ASPIC/UnbV
Type: Domain
Description: This conserved sequence is found associated with in several paralogous proteins in Rhodopirellula baltica. It is also found associated with in several eukaryotic integrin-like proteins (e.g. human ASPIC ) and in several other bacterial proteins (e.g. ) [ ].
Protein Domain
Name: E3 ubiquitin-protein ligase RKP, N-terminal
Type: Domain
Description: This domain represents the N-terminal region of the E3 ubiquitin-protein ligase RKP and other B30.2/SPRY domain-containing proteins from plants. RKP is an E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of KRP1 and KRP2 [ , ].
Protein Domain
Name: Gtt2-like, C-terminal
Type: Domain
Description: This entry represents the C-terminal GST-like alpha helical domain found in the budding yeast Gtt2 protein. Gtt2 is a glutathione S-transferase involved in the glutaredoxin-mediated antioxidant activity [ ]. Proteins containing this domain also include some bacterial GST-like proteins.
Protein Domain
Name: E3 ubiquitin-protein ligase BOI-like
Type: Family
Description: This family represents a group of proteins including E3 ubiquitin-protein ligases related to BOI (Botrytis Susceptible1 Interactor), which is involved in the regulation of pathogen and abiotic stress responses [ ]. This entry also includes some uncharacterised RING finger proteins.
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