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Search results 6701 to 6800 out of 30763 for seed protein

Category restricted to ProteinDomain (x)

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Categories

Category: ProteinDomain
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Type Details Score
Protein Domain
IPR022715
Name: Protein of unknown function DUF2671
Type: Family
Description: This group of proteins with unknown function is predominantly found in Rickettsiales.
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Protein Domain
IPR022718
Name: Protein of unknown function DUF2672
Type: Family
Description: This group of proteins with unknown function appears to be restricted to Rickettsiaceae.
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Protein Domain
IPR022719
Name: Gliding motility-associated protein GldM, C-terminal
Type: Domain
Description: This domain is found in bacteria at the C terminus of the GldM protein. This domain is typically between 169 to 182 amino acids in length and has two completely conserved residues (Y and N) that may be functionally important. GldM, is named for the member from Bacteriodetes Flavobacterium johnsoniae, which is required for a type of rapid gliding motility found in certain members of the Bacteriodetes [ ].
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Protein Domain
IPR009749
Name: Protein of unknown function DUF1315
Type: Family
Description: This family consists of several bacterial proteins of around 90 residues in length. The function of this family is unknown.
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Protein Domain
IPR010738
Name: Protein of unknown function DUF1310
Type: Family
Description: This family consists of several hypothetical proteins of around 125 residues in length. Members of this family seem to be specific to Firmicutes and Actinobacteria. The function of this family is unknown.
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Protein Domain
IPR022704
Name: Protein of unknown function DUF2746
Type: Family
Description: This entry represents proteins found in tailed bacteriophages and some species of Actinomicetes, including Gene 30 protein from Mycobacterium phage D29. Proteins in this entry are uncharacterised.
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Protein Domain
IPR010707
Name: Protein of unknown function DUF1285
Type: Family
Description: This family consists of several hypothetical bacterial proteins. The structure of some members has been solved but the function of this family is still unknown [ ].
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Protein Domain
IPR010710
Name: Protein of unknown function DUF1289
Type: Family
Description: This family consists of a number of hypothetical bacterial proteins. The aligned region spans around 56 residues and contains 4 highly conserved cysteine residues towards the N terminus. The function of this family is unknown.
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Protein Domain
IPR010718
Name: Protein of unknown function DUF1294
Type: Family
Description: This family includes a number of hypothetical bacterial and archaeal proteins of unknown function.
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Protein Domain
IPR007355
Name: Protein of unknown function DUF424
Type: Family
Description: Members of this family of uncharacterised proteins are found in bacteria and archaea.
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Protein Domain
IPR007353
Name: Protein of unknown function DUF421
Type: Family
Description: This family of uncharacterised proteins is known as YDFR family
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Protein Domain
IPR007352
Name: Protein of unknown function DUF420
Type: Family
Description: This is a predicted membrane protein with four transmembrane helices.
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Protein Domain
IPR019332
Name: Organic solute carrier protein 1
Type: Family
Description: Organic solute carrier protein 1, or Oscp1, is a family of proteins conserved from plants to humans. It is called organic solute transport protein or oxido-red-nitro domain-containing protein 1, however no reference could be find to confirm the function of the protein.
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Protein Domain
IPR020338
Name: SMN complex, gem-associated protein 7
Type: Family
Description: Gem-associated protein 7 (Gemin7) is a component of the survival of motor neuron complex, which functions in the assembly of spliceosomal small nuclear ribonucleoproteins. Gemin7 interacts with several Sm proteins of spliceosomal small nuclear ribonucleoproteins, especially SmE [ ]. Gem-associated protein 7 is found in the nucleoplasm, in nuclear "gems"(Gemini of Cajal bodies), and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene [ ].
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Protein Domain
IPR032318
Name: Protein of unknown function DUF4848
Type: Family
Description: A small family of uncharacterised proteins around 310 residues in length and found mainly in various Bacteroidales species. The function of this family is unknown.
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Protein Domain
IPR032316
Name: Protein of unknown function DUF4847
Type: Family
Description: Uncharacterized proteins in this family conserved in Bacteroidetes are similar to Shigella flexneri MxiM, a pilot protein for S. flexneri MxiD, an outer membrane (OM)-associated ring-forming secretin and component of the type-III secretion system. MxiM, also an OM protein, binds lipids and MxiD. This subgroup belongs to the lipocalin/cytosolic fatty-acid binding protein family which have a large β-barrel ligand-binding cavity [ , ].
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Protein Domain
IPR032315
Name: Protein of unknown function DUF4846
Type: Family
Description: This family consists of uncharacterised proteins around 260 residues in length found in bacteria. Its function is unknown.
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Protein Domain
IPR032314
Name: Protein of unknown function DUF4845
Type: Family
Description: This family consists of uncharacterised proteins around 120 residues in length and mainly found in Proteobacteria. Distant homology analysis suggests that proteins from this family are related to pilin type IV proteins from the Bundlin ( ) family; this prediction is however not confirmed by any experimental evidence.
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Protein Domain
IPR007366
Name: Protein of unknown function DUF432
Type: Family
Description: This is an archaeal protein of unknown function.
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Protein Domain
IPR007362
Name: Protein of unknown function DUF429
Type: Family
Description: This is a family of uncharacterised proteins.
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Protein Domain
IPR007367
Name: Protein of unknown function DUF433
Type: Family
Description: This entry includes a group of uncharacterised proteins, including VapB45 from Mycobacterium tuberculosis. VapB45 is possibly the antitoxin component of a type II toxin-antitoxin (TA) module. Its cognate toxin is VapC45 [ ].
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Protein Domain
IPR020323
Name: Protein of unknown function DUF2716
Type: Family
Description: This entry represents a group of uncharacterised proteins.
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Protein Domain
IPR008886
Name: Uncharacterised protein family UPF0227/Esterase YqiA
Type: Family
Description: Despite being classed as uncharacterised proteins, the members of this family are almost certainly enzymes in that contain a domain distantly related to . One of the members of this family YqiA has been shown to be a esterase [ ]. Other members, which include the Escherichia coli (strain K12) YcfP protein, are uncharacterised.
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Protein Domain
IPR022986
Name: Uncharacterised protein family UPF0237, ACT-type
Type: Family
Description: The proteins in this entry are functionally uncharacterised. They contain an ACT domain; ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. The ACT domain is found in a variety of contexts and is proposed to be a conserved regulatory binding fold [ ].
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Protein Domain
IPR019346
Name: 39S ribosomal protein L42, mitochondrial
Type: Family
Description: This entry represents a family of short proteins; each approximately 100 amino acid residues in length. They are identified as the mitochondrial 39S ribosomal protein L42.
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Protein Domain
IPR032301
Name: Protein of unknown function DUF4844
Type: Family
Description: This family consists of short uncharacterised proteins found mostly in different strains of Acinetobacter bumanii, but also in several Shewanella species and in some bacteria from the CFB group. Solved structure of ABAYE3784 protein from Acinetobacter baumannii AYE ( ) shows a five helical bundle with a very strong structural similarity to a bromodomain domain. However, the specific function of proteins from this family is unknown.
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Protein Domain
IPR007332
Name: Protein of unknown function DUF411
Type: Family
Description: The function of the members of this bacterial protein family is unknown. Some members may be involved in conferring cation resistance.
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Protein Domain
IPR009999
Name: Protein of unknown function DUF1514
Type: Family
Description: This entry includes Bacteriophage phi PVL, Orf60. The characteristics of the protein distribution suggest prophage matches in addition to the phage matches.This family consists of several Staphylococcus aureus and related bacteriophage proteins of around 65 residues in length. The function of this family is unknown.
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Protein Domain
IPR007338
Name: Protein of unknown function DUF416
Type: Family
Description: This is a bacterial family of uncharacterised proteins.
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Protein Domain
IPR007335
Name: Protein of unknown function DUF413
Type: Family
Description: This is a family of uncharacterised proteins.
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Protein Domain
IPR009995
Name: Protein of unknown function DUF1512
Type: Family
Description: This family consists of several archaeal proteins of around 370 residues in length. The function of this family is unknown.
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Protein Domain
IPR019311
Name: Protein of unknown function DUF2362
Type: Family
Description: This is a family of proteins conserved from nematodes to humans. The function is not known.
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Protein Domain
IPR020312
Name: Protein of unknown function DUF5497
Type: Family
Description: This is a family of unknown function found in Alphabaculovirus. It includes the ECORI-T site protein ETS, which was identified as a 1.7-kb transcript from the coding region within the EcoRI T fragment (29.0 to 30.1 map units) in Autographa californica nuclear polyhedrosis virus (AcMNPV) [ ]. This protein is produced as an early stage transcript and persists throughout infection, although its function is unknown [].
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Protein Domain
IPR046929
Name: Transposon related HTH domain protein
Type: Family
Description: This entry represents a bacterial family of proteins that is functionally uncharacterised. This protein contains a helix-turn-helix motif that is likely to be DNA-binding.
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Protein Domain
IPR007347
Name: Sporulation stage V, protein S
Type: Family
Description: In Bacillus subtilis this protein interferes with sporulation at an early stage and this inhibitory effect is overcome by SpoIIB and SpoVG. SpoVS seems to play a positive role in allowing progression beyond stage V of sporulation. Null mutations in the spoVS gene block sporulation at stage V, impairing the development of heat resistance and coat assembly [ ].
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Protein Domain
IPR020300
Name: Protein of unknown function DUF2644
Type: Family
Description: This family of proteins has no known function.
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Protein Domain
IPR020303
Name: Protein of unknown function DUF5495
Type: Family
Description: This is a family of unknown function found in Myoviridae.
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Protein Domain
IPR020370
Name: Protein of unknown function DUF5504
Type: Family
Description: This is a family of unknown function found in Lactobacillus. Family members have 4 predicted trans-membrane regions.
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Protein Domain
IPR020378
Name: Protein of unknown function DUF4186
Type: Family
Description: This protein family is functionally uncharacterised.
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Protein Domain
IPR020379
Name: Protein of unknown function DUF5448
Type: Family
Description: This is a family of unknown function found in Gammaproteobacteria.
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Protein Domain
IPR044332
Name: Accessory protein NS7a, deltacoronavirus, HKU30-like
Type: Domain
Description: This entry includes the accessory protein NS7a from Quail deltacoronavirus (QdCoV) UAE-HKU30 and sparrow deltacoronavirus (SpCoV-HKU17) within the Buldecovirus subgenus of deltacoronaviruses. In deltaCoVs, several avian species encode accessory protein NS7a, which is homologous to Porcine coronavirus (PDCoV) HKU15 accessory proteins NS7 and NS7a. PDCoV NS7a is a 100 amino-acid polypeptide identical to the C-terminal of NS7; it remains unclear whether their functions are redundant. The PDCoV NS7 protein is extensively distributed in the mitochondria and may be involved in various cellular processes such as cytoskeleton networks and cell communication, metabolism, and protein biosynthesis. NS7a proteins in this subfamily have yet to be characterised. Phylogenetic analysis revealed that QdCoV UAE-HKU30 belongs to the same CoV species as porcine deltacoronavirus (PdCoV) HKU15 and sparrow deltacoronavirus (SpdCoV) HKU17 within Buldecovirus subgenus, suggesting transmission between avian and swine hosts [ , , , ].
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Protein Domain
IPR019372
Name: Lipoma HMGIC fusion partner-like protein
Type: Family
Description: This is a group of proteins expressed from a series of genes referred to as Lipoma HMGIC fusion partner-like. The proteins carry four highly conserved transmembrane domains. In certain instances, as in LHFPL5, mutations cause deafness in humans [ ] or hypospadias []. LHFPL1 is transcribed in six liver tumour cell lines [].
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Protein Domain
IPR032358
Name: Protein of unknown function DUF4867
Type: Family
Description: This family consists of uncharacterised proteins around 220 residues in length and is mainly found in various human gut Firmicutes and a few eubacteria species. It is also amply represented in human gut metagenomic datasets. The function of this family is not clear.
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Protein Domain
IPR032357
Name: Protein of unknown function DUF4866
Type: Family
Description: This family consists of uncharacterised proteins around 250 residues in length and is mainly found in various human gut Firmicutes species and abundant in human gut metagenomic datasets. The function of this family is unknown.
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Protein Domain
IPR032344
Name: Protein of unknown function DUF4862
Type: Family
Description: This family consists of uncharacterised proteins around 300 residues in length and is mainly found in various high GC Gram-positive bacteria, but also in several pathogenic and non-pathogenic enterobacteria (Salmonella, E. coli). The function of this family is not clear.
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Protein Domain
IPR032342
Name: Protein of unknown function DUF4861
Type: Family
Description: This family consists of uncharacterised proteins around 400 residues in length and is mainly found in various Bacteroides species. The function of this family is unknown.
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Protein Domain
IPR032340
Name: Protein of unknown function DUF4860
Type: Family
Description: This family consists of uncharacterised proteins around 160 residues in length and is mainly found in various Firmicutes. The function of this family is unknown.
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Protein Domain
IPR032349
Name: Protein of unknown function DUF4865
Type: Family
Description: This family consists of uncharacterised proteins around 180 residues in length found in bacteria. The function of this family is not clear.
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Protein Domain
IPR032347
Name: Protein of unknown function DUF4864
Type: Family
Description: This family consists of uncharacterised proteins around 120 residues in length and is mainly found in bacteria and archaea.
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Protein Domain
IPR032345
Name: Protein of unknown function DUF4863
Type: Family
Description: This family consists of uncharacterised proteins around 150 residues in length and is mainly found in various proteobacteria, but also several fungal species. The function of this family is not clear.
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Protein Domain
IPR032333
Name: Protein of unknown function DUF4857
Type: Family
Description: This family consists of uncharacterised proteins around 340 residues in length and is mainly found in various bacteria. The function of this family is unknown.
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Protein Domain
IPR032331
Name: Protein of unknown function DUF4856
Type: Family
Description: This family consists of uncharacterised proteins around 400 residues in length and is mainly found in various Bacteroidetes and Proteobacteria species. The function of this family is unknown.
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Protein Domain
IPR005692
Name: Chloroplast protein import component Tic22
Type: Family
Description: Chloroplast function requires the import of nuclear encoded proteins from the cytoplasm across the chloroplast double membrane. This is accompished by two protein complexes, the Toc complex located at the outer membrane and the Tic complex loacted at the inner membrane [ ]. The Toc complex recognises specific proteins by a cleavable N-terminal sequence and is primarily responsible for translocation through the outer membrane, while the Tic complex translocates the protein through the inner membrane.This entry represents Tic22, a core member of the Tic complex. Tic22 is a soluble protein and the only Tic complex component of the intermembrane space that has been shown to interact with preproteins during import. It may also act as a chaperone that prevent misfolding or missorting of the preprotein to the intermembrane space and potentially serve as a component that links the Toc and Tic complexes [ ].
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Protein Domain
IPR032338
Name: Protein of unknown function DUF4858
Type: Family
Description: This family consists of uncharacterised proteins around 190 residues in length and is mainly found in various Bacteroides species. The function of this family is unknown.
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Protein Domain
IPR032322
Name: Protein of unknown function DUF4850
Type: Family
Description: This family consists of several uncharacterised proteins around 250 residues in length and is mainly found in various Acinetobacter species. The function of this family is unknown.
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Protein Domain
IPR007385
Name: Prokaryotic chromosome segregation/condensation protein MukE
Type: Family
Description: MukE is involved in the segregation and condensation of prokaryotic chromosomes. MukE along with MukF ( ) interact with MukB ( ) in vivo forming a complex, which is required for chromosome condensation and segregation in Escherichia coli [ ]. The Muk complex appears to be similar to the SMC-ScpA-ScpB complex in other prokaryotes where MukB is the homologue of SMC []. ScpA () and ScpB ( ) have little sequence similarity to MukE or MukF, though they are predicted to be structurally similar, being predominantly α-helical with coiled coil regions.
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Protein Domain
IPR007384
Name: Protein of unknown function UCP006257
Type: Family
Description: This family of uncharacterised conserved proteins includes YqcC from Escherichia coli.
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Protein Domain
IPR020343
Name: Viral CC chemokine-like protein FPV060
Type: Family
Description: Members of this family found in Fowlpox virus are CC chemokine-like proteins. Fpv060 contains the conserved pattern of four cysteine residues similar to the CC chemokine family. Fpv060 also contains more cysteines in the mature protein than cellular chemokines, and one predicted trans-membrane region. In vitro studies show N-terminal glycosylation and show that Fpv060 from Fowl pox virus is much larger and has many more cysteine residues than host chemokines and viral homologues [ ].
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Protein Domain
IPR020347
Name: Ribonucleases P/MRP protein subunit Pop8
Type: Family
Description: Pop8 is a component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. It is also a component of Ribonuclease MRP, which cleaves pre-rRNA sequences [ ]. Ribonuclease P consists of an RNA moiety and at least 9 protein subunits including POP1, POP3, POP4, POP5, POP6, POP7, POP8, RPP1 and RPR2. Ribonuclease MRP complex consists of an RNA moiety and at least 10 protein subunits including POP1, POP3, POP4, POP5, POP6, POP7, POP8, RMP1, RPP1 and SNM1, many of which are shared with the Ribonuclease P complex. This protein is found at the nucleus. Pop8 interacts with Pop5 and RPP1 to form the Pop5-Pop8-(RPP1)2 heterotetramer, which is part of thearm module of the p[protein hook [ ].
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Protein Domain
IPR007390
Name: Sporulation stage V, protein R
Type: Family
Description: One of the family members is Bacillus subtilis stage V sporulation protein R, which is involved in spore cortex formation [ ]. Little is known about cortex biosynthesis, except that it depends on several sigma E controlled genes, including spoVR [].
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Protein Domain
IPR032329
Name: Protein of unknown function DUF4855
Type: Family
Description: This family consists of uncharacterised proteins around 400 residues in length and is mainly found in various Bacteroides and Paenibacillus species.
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Protein Domain
IPR032327
Name: Protein of unknown function DUF4854
Type: Family
Description: This family consists of uncharacterised proteins found in firmicutes and high GC Gram-positive bacteria associated with human and animal guts. The function of this family is unknown.
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Protein Domain
IPR032326
Name: Protein of unknown function DUF4853
Type: Family
Description: This family consists of uncharacterised proteins around 220 residues in length and is mainly found in various Actinomyces species. The function of this family is unknown.
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Protein Domain
IPR032325
Name: Protein of unknown function DUF4852
Type: Family
Description: This family consists of several uncharacterised proteins around 350 residues in length and is mainly found in various bacteria. The function of this family is unknown.
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Protein Domain
IPR017082
Name: Ribosomal protein S23, mitochondrial, fungi
Type: Family
Description: Rsm23 is a mitochondrial ribosomal protein of the small subunit. It is required for maintenance of mitochondrial DNA [ ].
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Protein Domain
IPR032323
Name: Protein of unknown function DUF4851
Type: Family
Description: This family consists of several uncharacterised proteins around 250 residues in length and is mainly found in various Desulfovibrio species. The function of this family is unknown.
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Protein Domain
IPR032388
Name: Flagellar assembly protein T, C-terminal
Type: Domain
Description: This entry represents the C-terminal domain of a family of flagellar (FlgT) proteins that make up part of the basal body of the flagellum. FlgT is composed of three domains, the N-terminal domain (FlgT-N), the middle domain (FlgT-M), and the C-terminal domain (FlgT-C). The flagellum is a large macromolecular assembly composed of three major parts: the basal body, the hook, and the filament. The basal body has two unique ring structures, the T ring and the H ring. FlgT is required to form and stabilise both ring structures. FlgT-C is made up of seven β-strands and a helical segment, arranged in a core β-barrel structure and a β-hairpin. The C-terminal domain of FlgT is not essential but stabilises the H-ring structure [ ].
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Protein Domain
IPR032384
Name: Kinesin-like protein Kif23, Arf6-interacting domain
Type: Domain
Description: This entry represents a C-terminal region of kinesin-like protein Kif23 (also known as MKLP1) that is necessary for the interaction with the small GTPase Arf6. MKLP1 is a Flemming body-localising protein essential for cytokinesis. The Arf6-MKLP1 complex plays a crucial role in cytokinesis by connecting the microtubule bundle and membranes at the cleavage plane [ ].
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Protein Domain
IPR032383
Name: Protein of unknown function DUF4875
Type: Family
Description: This small protein family has members present in few proteobacteria, mostly Desulfovibrio species, but also in Vibrio phage vB, suggesting a possible phage origin. The experimentally determined structure shows a fold reminiscent of a thioesterase/thiol ester dehydrase-isomerase fold (PDB entry 4lg3), but the functional consequences of this similarity are not clear.
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Protein Domain
IPR032370
Name: Flagellar assembly protein T, N-terminal
Type: Domain
Description: This entry represents the N-terminal domain of FlgT, a flagellar protein that make up part of the basal body of the flagellum. The flagellum is a large macromolecular assembly composed of three major parts: the basal body, the hook, and the filament. The basal body has two unique ring structures, the T ring and the H ring. FlgT is required to form and stabilise both ring structures. FlgT is composed of three domains, the N-terminal domain (FlgT-N), the middle domain (FlgT-M), and the C-terminal domain (FlgT-C). This N-terminal domain contributes to the construction of the H-ring structure, and adopts a two-layer α-β sandwich architecture composed of a four-stranded anti-parallel β-sheet and two alpha helices [ ].
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Protein Domain
IPR020394
Name: Uncharacterised protein family, FAM23-like, transmembrane
Type: Family
Description: This entry represents a group of uncharacterised transmembrane proteins that are members of the FAM23 family of proteins.
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Protein Domain
IPR032366
Name: Protein of unknown function DUF4871
Type: Family
Description: This family consists of uncharacterised proteins around 170 residues in length and is mainly found in various Bacillus species (B. cereus, B. thuringiensis and B. anthracis). The solved structure of B. anthracis homologues (PDB entry 4JG9) has a variant of the Greek-key beta barrel fold. The function of this family is not clear.
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Protein Domain
IPR032360
Name: Protein of unknown function DUF4869
Type: Family
Description: This family consists of uncharacterised proteins around 150 residues in length. Its members are found in human gut Firmicutes and are also abundant in human gut metagenomics datasets. The function of this family is unknown.
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Protein Domain
IPR044394
Name: Structural accessory protein ORF7b, SARS-CoV-like
Type: Family
Description: This entry contains the ORF7b, also called NS7b, of Severe Acute Respiratory Syndrome coronaviruses (SARS-CoVs) and related betacoronaviruses identified in Chinese horseshoe bats, including bat SARS-like-CoV WIV1 and HKU3.ORF7b/NS7b from betacoronavirus in the B lineage are not related to NS7b proteins from other betacoronavirus lineages. The SARS-CoV ORF7b protein is a 44 amino acid protein which is homologous to an accessory but structural component of SARS-CoV virion. While ORF7b is packaged into virions, it is not required for the virus budding process, as gene 7 deletion viruses replicate efficiently in vitro and in vivo. Moreover, ORF7b possesses a transmembrane helical domain (TMD), between 9-29 amino acid residues, is necessary for its Golgi complex localization, as replacing it with the TMD from the human endoprotease furin results in aberrant localization [ , ].
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Protein Domain
IPR021532
Name: Structural accessory protein ORF7b, betacoronavirus
Type: Family
Description: This entry corresponds to ORF7b (also known as accessory protein 7b, NS7B, and 7b) from human SARS coronavirus (SARS-CoV) and SARS-CoV-2, which belong to the betacoronavirus B lineage (Sarbecovirus) [ ].ORF7b/NS7b from betacoronavirus in the B lineage are not related to NS7b proteins from other betacoronavirus lineages. The SARS-CoV ORF7b protein is a 44 amino acid protein which is homologous to an accessory but structural component of SARS-CoV virion. While ORF7b is packaged into virions, it is not required for the virus budding process, as gene 7 deletion viruses replicate efficiently in vitro and in vivo. Moreover, ORF7b possesses a transmembrane helical domain (TMD), between 9-29 amino acid residues, is necessary for its Golgi complex localization, as replacing it with the TMD from the human endoprotease furin results in aberrant localization [ , ].ORF7b from SARS-CoV-2 is a 43 amino acid protein localized in the membrane of the endoplasmic reticulum and it has been shown to induce apoptosis. It promotes expression of IFN-beta, TNF-alpha, and IL-6, and activation of type-I IFN signaling through IRF3 phosphorylation and to activate TNFalpha-induced apoptosis in HEK293T cells and Vero E6 cells [ , ]. These recent findings suggest a mechanism to understand pathogenicity of SARS-CoV-2 and the role of its accessory proteins in modulating host immune responses.
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Protein Domain
IPR007407
Name: Protein of unknown function DUF459
Type: Family
Description: This is a putative periplasmic protein and a member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases [ ].
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Protein Domain
IPR007403
Name: Protein of unknown function DUF456
Type: Family
Description: This is a family of putative membrane proteins.
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Protein Domain
IPR007401
Name: Protein of unknown function DUF454
Type: Family
Description: This entry includes YbaN from Escherichia coli. It is an inner membrane protein.
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Protein Domain
IPR007408
Name: Protein of unknown function DUF460
Type: Family
Description: This is an archaeal protein of unknown function.
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Protein Domain
IPR007432
Name: Protein of unknown function DUF480
Type: Family
Description: This family consists of several proteins of uncharacterised function.
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Protein Domain
IPR023491
Name: Acyl carrier protein phosphodiesterase, gammaproteobacteria
Type: Family
Description: This entry contains the Acyl carrier protein phosphodiesterase (AcpH, also called ACP hydrolyase) from Escherichia coli. Proteins in this entry are restricted to the gammaproteobacteria. AcpH converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP [ , ].A mutant E. coli strain having a total deletion of the acpH grows normally, showing that phosphodiesterase activity is not essential for growth, although it is required for turnover of the ACP prosthetic group in vivo. AcpH is found only in Gram-negative organisms suggesting that it plays a role in some aspect of lipid metabolism that is unique to these organisms. The most obvious of which is biosynthesis of lipid A. Because AcpH is a hydrolase, it could possibly be an editing enzyme that intercepts acyl-ACPs that would give an inappropriate lipid A structure if used as acyl donors [ ].
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Protein Domain
IPR007437
Name: Protein of unknown function DUF486
Type: Family
Description: This family contains several proteins of uncharacterised function. The family is represented in the Transport classification database as 2.A.7.34, though the exact nature of what is transported is not known.
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Protein Domain
IPR007436
Name: Protein of unknown function DUF485
Type: Family
Description: This family includes several putative integral membrane proteins.
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Protein Domain
IPR007435
Name: Protein of unknown function DUF484
Type: Family
Description: This family consists of several proteins of uncharacterised function.
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Protein Domain
IPR019416
Name: Nuclear cap-binding protein subunit 3
Type: Family
Description: The cap-binding complex (CBC) consisting of NCBP2 and its adaptor NCBP1 is believed to bind all capped RNA and to be necessary for its processing and intracellular localisation. Nuclear cap-binding protein subunit 3 (NCBP3), together with NCBP1, forms an alternative CBC in higher eukaryotes. NCBP3 binds mRNA, associates with components of the mRNA processing machinery and contributes to poly(A) RNA export [ ].
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Protein Domain
IPR020404
Name: Protein of unknown function DUF2713
Type: Domain
Description: This entry contains proteins with no known function. In some organisms this represents the C-terminal domain of a fusion protein with YjbL.
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Protein Domain
IPR007418
Name: Protein of unknown function DUF474
Type: Family
Description: This is a family of uncharacterised archaeal/bacterial proteins.They are predicted to be integral membrane proteins with several transmembrane segments.
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Protein Domain
IPR007417
Name: Protein of unknown function DUF473
Type: Family
Description: This is a family of uncharacterised archaeal proteins.
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Protein Domain
IPR007414
Name: Protein of unknown function DUF468
Type: Family
Description: This is a family of uncharacterised yeast proteins.
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Protein Domain
IPR007420
Name: Protein of unknown function DUF465
Type: Family
Description: Family members are found in small bacterial proteins, and also in the heavy chains of fungal proteins that contain the domain kinesin, in which this region is located C-terminal of the motor domain. Members of this family may form coiled coil structures [ ].
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Protein Domain
IPR007429
Name: Protein of unknown function DUF478
Type: Family
Description: This family contains uncharacterised protein encoded on Trypanosomal kinetoplast minicircles.
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Protein Domain
IPR007427
Name: Protein of unknown function DUF475
Type: Family
Description: This entry contains proteins that are predicted to be an integral membrane proteins with multiple transmembrane domains.
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Protein Domain
IPR009898
Name: Protein of unknown function DUF1440
Type: Family
Description: This family contains a number of bacterial proteins of unknown function approximately 180 residues long. These are possibly integral membrane proteins [ ].
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Protein Domain
IPR010889
Name: Protein of unknown function DUF1515
Type: Family
Description: This family consists of several hypothetical bacterial proteins of around 130 residues in length. Members of this family seem to be found exclusively in Rhizobium species. The function of this family is unknown.
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Protein Domain
IPR009895
Name: Protein of unknown function DUF1438
Type: Family
Description: This family consists of several hypothetical proteins of around 170 residues in length predominantly found in rodents. The function of this family is unknown.
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Protein Domain
IPR020210
Name: Uncharacterised protein family, YpbF, transmembrane
Type: Family
Description: This entry represents a group of uncharacterised transmembrane proteins.
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Protein Domain
IPR022877
Name: Protein of unknown funcion UPF0173
Type: Family
Description: This entry represents a group of uncharacterised proteins that belong to the UPF0173 family of metal-dependent hydrolases predominantly found in bacteria and archaea.
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Protein Domain
IPR019218
Name: Protein of unknown function DUF2119
Type: Family
Description: This entry represents a family of hypothetical archaeal proteins of unknown function.
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Protein Domain
IPR019219
Name: Protein of unknown function DUF2130
Type: Family
Description: This entry, found in various hypothetical bacterial proteins, has no known function.
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Protein Domain
IPR019217
Name: Protein of unknown function DUF2118
Type: Family
Description: This entry represents a family of hypothetical proteins of unknown function.
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