Protein Domain : Centrosome-associated protein 350 IPR028750

Type  Family
Description  Centrosome-associated protein 350 (CEP350 or CAP350) plays an essential role in centriole growth by stabilising a procentriolar seed composed of, at least, SASS6 and CENPJ [ ]. It is required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network []. It also stabilises Golgi-associated microtubules and maintains a continuous pericentrosomal Golgi ribbon [].CEP350 possesses a CAP-Gly domain which is targeted to the centrosome or the Golgi-like network and binds microtubules through an N-terminal basic region [ ].
Short Name  CEP350

0 Child Features

0 Gene Families

0 Genes

3 Ontology Annotations

0 Parent Features

0 Publications

USDA
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