GO Term : GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity Gene Ontology

Description  Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.
Namespace  molecular_function
Obsolete  false

0 Cross References

8 Data Sets

Trail: GOTerm

1 Ontology

Trail: GOTerm

25 Ontology Annotations

Trail: GOTerm

9 Parents

Trail: GOTerm

9 Relations

Trail: GOTerm

15 Synonyms

Trail: GOTerm
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