GO Term : GO:0036316 SREBP-SCAP complex retention in endoplasmic reticulum Gene Ontology

Description  Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which retain the complex in the ER.
Namespace  biological_process
Obsolete  false

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1 Ontology

Trail: GOTerm

0 Ontology Annotations

119 Parents

Trail: GOTerm

192 Relations

Trail: GOTerm

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