GO Term : GO:0036500 ATF6-mediated unfolded protein response Gene Ontology

Description  A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor ATF6 (activating transcription factor 6). Begins with activation of ATF6 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. Under conditions of endoplasmic reticulum stress, ATF6 translocates to the Golgi where it is processed by proteases to release a cytoplasmic domain (ATF6f), which operates as a transcriptional activator of many genes required to restore folding capacity.
Namespace  biological_process
Obsolete  false

0 Cross References

0 Data Sets

1 Ontology

Trail: GOTerm

0 Ontology Annotations

24 Parents

Trail: GOTerm

36 Relations

Trail: GOTerm

8 Synonyms

Trail: GOTerm
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