v5.1.0.3
Cicer data from the Legume Information System
Type | Family |
Description | This entry includes E3 ubiquitin ligase UBR4 from animals, auxin transport protein BIG from plants and protein purity of essence from fruit flies.UBR4, also known as p600, is a member of the N-recognin family, which contains proven and predicted E3 ligases that recognise and degrade proteins containing destabilising N termini [ ]. It is involved in anoikis, viral transformation and protein degradation [, ]. It also has roles in neurogenesis, neuronal migration, neuronal signaling and survival in mammalian brains [].BIG is required for auxin efflux and polar auxin transport (PAT) influencing auxin-mediated developmental responses (e.g. cell elongation, apical dominance, lateral root production, inflorescence architecture, general growth and development) [ ]. Auxin transport protein is also involved in the elongation of the pedicels and stem internodes through auxin action, the expression/modulation of light-regulated genes, repression of CAB1 and CAB3 genes in etiolated seedlings, etc [ , , , , , , , ].Protein purity of essence, found in Drosophila melanogaster, has a role in growth of the perineurial glial layer of the larval peripheral nerve and it may have a role in male fertility and eye development or function [, , ]. |
Short Name | UBR4-like |