v5.1.0.3
Cicer data from the Legume Information System
Type | Family |
Description | Mitochondria-eating protein (MIEAP, also known as spermatogenesis-associated protein 18), a p53-inducible protein, is a key regulator of mitochondrial quality that mediates the repair or degradation of unhealthy mitochondria in response to mitochondrial damage [ ]. It induces intra-mitochondrial lysosome-like organella that eliminate oxidised mitochondrial proteins without destroying the mitochondrial structure, leading to improvement in mitochondrial function []. It is also involved in degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade the mitochondria by accumulating lysosomes []. |
Short Name | MIEAP |