v5.1.0.3
Cicer data from the Legume Information System
Type | Family |
Description | Trypanosoma brucei is the causative agent of sleeping sickness in humans and nagana in cattle. The parasite lives extracellularly in the blood and tissue fluids of the mammalian host, and is transmitted by the bite of infected tsetse. Each variant surface glycoprotein (Vsg) expression site (ES) in bloodstream-form T. brucei is a polycistronic transcription unit containing several distinct expression site-associated genes (esag), in addition to a single vsg gene. They are co-transcribed with the gene encoding the VSG protein, forming the surface coat of the parasite. ESAG1 genes from different ESs encode a highly polymorphic family of membrane-associated glycoproteins, whose function is unknown [ ]. |
Short Name | ESAG |