Protein Domain : Vacuolar protein sorting-associated protein Vta1-like IPR044538

Type  Family
Description  This entry represents yeast Vta1 and its homologues from animals and plants. Vta1 interacts with the AAA ATPase Vps4 and is required for multivesicular body (MVB) sorting [ , ]. This entry also includes LIP5 from Arabidopsis. LIP5 is a positive regulator of the Suppressor of K(+) Transport Growth Defect1 (SKD1) AAA ATPase in MVB biogenesis. It is also a target of pathogen-responsive mitogen-activated protein kinases (MPKs) and plays a critical role in plant basal resistance [, ]. Mammalian Vta1 homologue functions in MVB sorting and is required for HIV release [].
Short Name  Vta1-like
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