Protein Domain : Tumour protein p53-inducible nuclear protein IPR029431

Type  Family
Description  This entry represents tumour protein p53-inducible nuclear protein 1 and 2 (Tp53inp1 and Tp53inp2). There is only DOR/Tp53inp2 in invertebrates, while both Tp53inp1 and Tp53inp2 can be found in vertebrates. The vertebrates Tp53inp1 gene may have arisen by gene duplication [ ]. Tumour protein p53-inducible nuclear protein 1 is an antiproliferative and proapoptotic protein involved in cell stress response. It acts as a dual regulator of transcription and autophagy [ ].DOR/TP53INP2 is a bifunctional protein that functions as a modulator of autophagy and in gene transcription [ ].
Short Name  TP53INP

0 Child Features

0 Gene Families

0 Genes

0 Ontology Annotations

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