Protein Domain : TIP41-like protein IPR007303

Type  Family
Description  In budding yeast, TIP41 interacts with TAP42 to regulate protein phosphatase activity [ ]. In mammalian cells, TIP41-like protein (TIPRL) does not directly bind TAP42, but rather primarily interacts with PP2A, PP4 or PP6 catalytic subunits. TIPRL inhibits PP4 activity to allow for H2AX phosphorylation and the subsequent DNA damage response [].
Short Name  TIP41-like

0 Child Features

1 Gene Families

6 Genes

1 Ontology Annotations

0 Parent Features

4 Publications

USDA
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