Protein Domain : Porin, gammaproteobacterial IPR001897

Type  Family
Description  Porins are found in the outer membranes of Gram-negative bacteria, mitochondria and chloroplasts, where they form ion-selective channels forsmall hydrophilic molecules (up to ~600 D) [ , ]. X-ray structure analysesof several bacterial porins [ , , ] have revealed a 16-stranded anti-parallelβ-barrel structure enclosing the transmembrane pore, by contrast with all other integral membrane proteins described to date, which are α-helical. Three subunits form a trimer; the 3-fold axis is approximatelyparallel to the barrel axes and is assumed to be perpendicular to the membrane plane.From the range of porins now known, similarities have been observed between porins from different species, and between porins of different specificitywithin the same species. But most porins cannot be related to each other on the basis of sequence alone, and this is reflected in the lengths of theknown porin sequences, which range from 282-483 residues/monomer.This entry is specific for porins in the gammaproteobacteria.
Short Name  Porin_gammaproteobac

0 Child Features

0 Gene Families

1 Genes

4 Ontology Annotations

1 Parent Features

1 Publications

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