Protein Domain : Acetoacetyl-CoA synthase IPR005914

Type  Family
Description  Isoprenoids are a large class of compounds, with more than 20,000 structures currently known, which are found in all living organisms. Some play essential physiological roles, such as sterols that stabilise cell membranes or carotenoids involved in photosynthesis, while the function of many others is not well understood. In all eukaryotes and some prokaryotes, isoprenoids are synthesised by the mevalonate pathway, while most prokaryotes use a mevalonate-independent pathway [ , ].This entry represents acetoacetyl-CoA synthase ( ), catalysing the first step of the mevalonate pathway of isoprenoid biosynthesis via isopentenyl diphosphate. ATP + acetoacetate + CoA = AMP + diphosphate + acetoacetyl-CoA A Sinorhizobium protein in this entry is also required for growth on polyhydroxybutyrate, a commonly used carbon storage molecule in bacteria [ ]. This entry also includes malonamoyl-CoA synthetase which in Penicillium is involved in the biosynthesis of the tetracycline-like viridicatumtoxin [].
Short Name  Acac_CoA_synth

0 Child Features

0 Gene Families

0 Genes

2 Ontology Annotations

0 Parent Features

0 Publications

USDA
InterMine logo
The Legume Information System (LIS) is a research project of the USDA-ARS:Corn Insects and Crop Genetics Research in Ames, IA.
LegumeMine || ArachisMine | CicerMine | GlycineMine | LensMine | LupinusMine | PhaseolusMine | VignaMine | MedicagoMine
InterMine © 2002 - 2022 Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom