Protein Domain : NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial IPR015828

Type  Family
Description  This entry represents the subunit 10 (also known as CI-42kD) of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). It is an accessory subunit that is believed not to be involved in catalysis [ ]. NADH:ubiquinone oxidoreductase (complex I) ( ) is a respiratory-chain enzyme that catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane (NADH + ubiquinone = NAD+ + ubiquinol) [ ]. Complex I is a major source of reactive oxygen species (ROS) that are predominantly formed by electron transfer from FMNH(2). Complex I is found in bacteria, cyanobacteria (as a NADH-plastoquinone oxidoreductase), archaea [], mitochondria, and in the hydrogenosome, a mitochondria-derived organelle. In general, the bacterial complex consists of 14 different subunits, while the mitochondrial complex contains homologues to these subunits in addition to approximately 31 additional proteins [].
Short Name  NDUFA10

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