LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | XPB/Ssl2 helicase (also known as Ercc3/RepB/XPB/Rad25/Ssl2/haywire) is a core subunit of the eukaryotic basal transcription factor complex TFIIH which plays a dual role in transcription and DNA repair [ ]. It is involved in nucleotide excision repair (NER) of DNA and in RNA transcription by RNA polymerase II []. The TFIIH multiprotein complex consists of a 7-subunit core (XPB, p62, p52, p44, p34, and TTDA) that is associated with a 3-subunit CDK-activating kinase module (MAT1, cyclin H and Cdk7) []. It acts by opening DNA either around the RNA transcription start site or the DNA damage []. Defects in XPB are the cause of xeroderma pigmentosum complementation group B (XP-B); also known as xeroderma pigmentosum II (XP2) or XP group B (XPB) or xeroderma pigmentosum group B combined with Cockayne syndrome (XP-B/CS) [ , ]. Defects in XPB are also a cause of trichothiodystrophy photosensitive (TTDP) []. |
| Short Name | XPB/Ssl2 |
