GO Term : GO:1990195 macrolide transmembrane transporter complex Gene Ontology

Description  A bacterial transmembrane transporter complex that spans the entire cell membrane system and possesses ATP-dependent xenobiotic transport activity pumping drugs (typically antibiotics) and other toxins directly from the cytosol out of the bacterial cell. Typically, it is trimeric consisting of a inner membrane ATPase (IMP), a periplasmic membrane fusion protein (MFP) and an outer membrane factor (OMF). In E. coli, macrolide transporter complexes may consists of MacB (IMP), MacA (MFP) and TolC (OMF) or AcrB (IMP), AcrA (MFP) and TolC (OMF). Trimeric TolC is a common OMF found in many macrolide transporter complexes.
Namespace  cellular_component
Obsolete  false

0 Cross References

1 Data Sets

Trail: GOTerm

1 Ontology

Trail: GOTerm

1 Ontology Annotations

Trail: GOTerm

10 Parents

Trail: GOTerm

11 Relations

Trail: GOTerm

4 Synonyms

Trail: GOTerm
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