GO Term : GO:0086024 adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate Gene Ontology

Description  An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of heart contraction. Binding of adrenalin or noradrenalin to a beta-adrenergic receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gs protein. Gs activates adenylate cyclase to increase intracellular cyclic-AMP (cAMP) levels. cAMP binds directly to F-channels to allow an inward flow of sodium (known as funny current, or If current). The funny current is responsible for membrane depolarization and an increase in heart rate.
Namespace  biological_process
Obsolete  false

0 Cross References

0 Data Sets

1 Ontology

Trail: GOTerm

0 Ontology Annotations

49 Parents

Trail: GOTerm

77 Relations

Trail: GOTerm

7 Synonyms

Trail: GOTerm
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