GO Term : GO:0003713 transcription coactivator activity Gene Ontology

Description  A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
Namespace  molecular_function
Obsolete  false

0 Cross References

8 Data Sets

Trail: GOTerm

1 Ontology

Trail: GOTerm

70 Ontology Annotations

Trail: GOTerm

4 Parents

Trail: GOTerm

5 Relations

Trail: GOTerm

6 Synonyms

Trail: GOTerm
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