GO Term : GO:0017101 aminoacyl-tRNA synthetase multienzyme complex Gene Ontology

Description  A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates.
Namespace  cellular_component
Obsolete  false

0 Cross References

1 Data Sets

Trail: GOTerm

1 Ontology

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2 Ontology Annotations

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4 Parents

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4 Relations

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2 Synonyms

Trail: GOTerm
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