GO Term : GO:0035329 hippo signaling Gene Ontology

Description  The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.
Namespace  biological_process
Obsolete  false

0 Cross References

1 Data Sets

Trail: GOTerm

1 Ontology

Trail: GOTerm

3 Ontology Annotations

Trail: GOTerm

12 Parents

Trail: GOTerm

20 Relations

Trail: GOTerm

6 Synonyms

Trail: GOTerm
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