GO Term : GO:0004839 ubiquitin activating enzyme activity Gene Ontology

Description  Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.
Namespace  molecular_function
Obsolete  false

0 Cross References

0 Data Sets

1 Ontology

Trail: GOTerm

0 Ontology Annotations

6 Parents

Trail: GOTerm

5 Relations

Trail: GOTerm

1 Synonyms

Trail: GOTerm
USDA
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