GO Term : GO:0097071 interferon regulatory factor complex Gene Ontology

Description  A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit.
Namespace  cellular_component
Obsolete  false

0 Cross References

0 Data Sets

1 Ontology

Trail: GOTerm

0 Ontology Annotations

3 Parents

Trail: GOTerm

7 Relations

Trail: GOTerm

1 Synonyms

Trail: GOTerm
USDA
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