Protein Domain : Periplasmic binding protein IPR025997

Type	Domain
Description	Bacterial high affinity transport systems are involved in active transport of solutes across the cytoplasmic membrane. Most of the bacterial ABC (ATP-binding cassette) importers are composed of one or two transmembrane permease proteins, one or two nucleotide-binding proteins and a highly specific periplasmic solute-binding protein. In Gram-negative bacteria the solute-binding proteins are dissolved in the periplasm, while in archaea and Gram-positive bacteria, their solute-binding proteins are membrane-anchored lipoproteins [ , ]. On the basis of sequence similarities, the vast majority of these solute-binding proteins can be grouped into eight family clusters [ ], which generally correlate with the nature of the solute bound. This entry represents the family 2 [, ]. Family 2 members include:Autoinducer 2-binding protein LsrB from E. coli and Salmonella typhimurium [ , ] D-galactose-binding periplasmic proteinAutoinducer 2-binding periplasmic protein LuxPD-ribose-binding periplasmic proteinMultiple sugar-binding periplasmic receptor ChvEThis entry represents a domain found in a variety of bacterial periplasmic binding proteins belonging mainly to family 2 which can recognise fructose [ ].
Short Name	SBP_2_dom