Protein Domain : AP-1 complex-associated regulatory protein IPR031483

Type  Family
Description  AP-1 complex-associated regulatory protein (AP1AR), also known as gadkin or gamma-BAR, is a negative regulator of the actin-related protein (ARP)2/3 complex, a major regulator of actin dynamics. Through inhibition of ARP2/3, gadkin negatively regulates cell spreading and motility [ ]. Gadkin is also a modulator of adaptor protein (AP)-1-mediated endosomal membrane trafficking [, , ].
Short Name  AP1AR

0 Child Features

0 Gene Families

0 Genes

5 Ontology Annotations

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0 Publications

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