Protein Domain : ATP-binding protein Uup IPR043686

Type	Family
Description	Uup is an ATP-binding cassette (ABC) protein of the F type (ABCF). It has ATPase activity and possesses two nucleotide binding domains which comprise Walker A/B motifs connected by a linker and a coiled-coil C-terminal domain. It binds double-stranded DNA with no sequence specificity [ ]. The Uup ATPase activity functions cooperatively thus the inactivation of one site suppresses all ATP hydrolytic activity []. It is implicated in precise excision of transposons. It bind to branched DNAs and is involved in resolution of branched DNA intermediates that result from template switching in post replication gaps [].It may also be involved in the 50S ribosome subunit assembly due to its genetic interaction with translational GTPase BipA [].
Short Name	Uup