Protein Domain : Autophagy-related protein 14 IPR023261

Type  Family
Description  Macroautophagy is a bulk degradation process induced by starvation in eukaryotic cells [ ]. In yeast, 15 autophagy (Apg) proteins coordinate the formation of autophagosomes. Apg14p and Vps30p/Apg6p, components of an autophagy-specific phosphatidylinositol 3-kinase complex, together with Apg9p and Apg16p, are required for localisation of Apg5p and Aut7p to a pre-autophagosome structure that functions in autophageosome formation [, ]. Mutations in the Saccharomyces cerevisiae APG14 gene have been shown to cause defects in autophagy [].
Short Name  Autophagy-related_protein_14

0 Child Features

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