Protein Domain : Retinal homeobox protein RAX/RAX2 IPR043562

Type  Family
Description  RAX is a transcription factor that plays a critical role in the eye and forebrain development of vertebrate species. It is involved in the establishment of the retina [ ]. Mutations in the RAX gene cause microphthalmia, isolated 3, which is a disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues []. Homeobox protein ceh-8 is the RAX orthologue from C. elegans required for cell specification of the RIA interneurons [].Retina and anterior neural fold homeobox protein 2 (RAX2) is known to bind to the Ret-1 and Bat-1 element within the rhodopsin promoter and may be involved in modulating the expression of photoreceptor specific genes [ ].This entry includes a group of homeobox proteins, including RAX and RAX2.
Short Name  RAX/RAX2

0 Child Features

0 Gene Families

0 Genes

2 Ontology Annotations

0 Parent Features

0 Publications

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