Protein Domain : Protein phosphatase Slingshot-like IPR043587

Type  Family
Description  Slingshot (SSH) is a cofilin-specific phosphatase. Dephosphorylation reactivates cofilin, which in turn depolymerizes actin and is thus required for actin filament reorganization [ ]. Slingshot is a member of the dual-specificity protein phosphatase family []. The N-terminal SSH region may be involved in P-cofilin binding (the model C terminus plus the DEK_C-like domain, which are characterized as the "B"domain in some of the literature), and may be required for the F-actin mediated activation of slingshot [ , ].
Short Name  Phosphatase_SSH-like

0 Child Features

0 Gene Families

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3 Ontology Annotations

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