Protein Domain : Protein polyglycylase TTLL10 IPR027752

Type  Family
Description  TTLL10 is a polyglycylase, which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the γ-carboxyl groups of specific glutamate residues of target proteins [ ]. It polyglycylates alpha tubulin and beta tubulin, but is not able to initiate glycylation and only has activity toward monoglycylated tubulin [ ]. It has the ability to polyglycylate non-tubulin proteins such as NAP1; in this case it can initiate glycylation and does not require preliminary monoglycylation by another glycylase [].This family also includes , which is inactive [ ].
Short Name  TTLL10

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