Protein Domain : Meiotic recombination protein Rec114 IPR004354

Type	Family
Description	This entry includes budding yeast Rec114 protein and its homologue, Rec7, from S. pombe. They are required for meiotic intragenic recombination but not for mitotic recombination [ , ]. REC114 is one of 10 genes required for initiation of meiotic recombination in Saccharomyces cerevisiae [ ]. Located on chromosome XIII, it is transcribed only in meiosis and has no detectable function in mitosis []. REC114 has been shown to possess an intron and is one of only three genes in yeast with 3' introns []. The 3' splice site utilised in REC114 is a very rare AAG sequence - only three other genes in yeast use this non-consensus sequence []. It appears that the intron is not essential for expression of REC114 and is not absolutely required for meiotic function. Nevertheless, it is conserved in evolution - two other species of yeast contain an intron at the same location in their REC114 genes [].
Short Name	Meiotic_Rec114