Protein Domain : F-box only protein 30/40 IPR031890

Type  Family
Description  This entry includes F-box only protein 30 (Fbxo30) [ ] and F-box only protein 40 (Fbxo40) []. Fbxo30 is a ubiquitin ligase required for muscle loss, hence it is also known as muscle ubiquitin ligase of the SCF complex in atrophy-1 (MUSA1) []. Fbxo40 id an E3 ubiquitin ligase that induces IRS1 ubiquitination and breakdown specifically in skeletal muscle cells and only upon IGF1 (insulin-like growth factor 1) stimulation [].
Short Name  Fbxo30/Fbxo40

0 Child Features

0 Gene Families

0 Genes

1 Ontology Annotations

0 Parent Features

0 Publications

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