Protein Domain : Synaptobrevin/Vesicle-associated membrane protein IPR016444

Type  Family
Description  This entry includes vesicle-associated membrane proteins VAMP1/synaptobrevin-1, VAMP2/synaptobrevin-2, VAMP3/synaptobrevin-3 and VAMP8/endobrevin.VAMPs are a group of small, integral membrane proteins of synaptic vesicles that is mostly involved in vesicle fusion. The heterotrimeric SNARE complex is formed by syntaxin 1, synaptosomal-associated protein 25kDa (SNAP25), and vesicle-associated membrane protein (VAMP)/synaptobrevin []. VAMP1 plays an essential, non-redundant role in Ca2+-triggered vesicle exocytosis at the mouse neuromuscular junction []. VAMP2 is extensively expressed in the central nervous system []. Neurotransmitter release involves the assembly of a heterotrimeric SNARE complex composed of SNAP25, VAMP2 and syntaxin 1 []. VAMP8 may be involved in regulated exocytosis of the exocrine system [, ].
Short Name  Synaptobrevin/VAMP

0 Child Features

0 Gene Families

0 Genes

0 Ontology Annotations

1 Parent Features

0 Publications

USDA
InterMine logo
The Legume Information System (LIS) is a research project of the USDA-ARS:Corn Insects and Crop Genetics Research in Ames, IA.
LegumeMine || ArachisMine | CicerMine | GlycineMine | LensMine | LupinusMine | PhaseolusMine | VignaMine | MedicagoMine
InterMine © 2002 - 2022 Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom