Protein Domain : Neurosecretory protein VGF IPR026128

Type  Family
Description  VGF protein is a neurosecretory protein originally identified as a product of the nerve growth factor responsivegene Vgf in rat pheochromocytoma PC12 cells [ , ]. VGF may be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system []. Neuroendocrine regulatory peptides (NERP)-1 and NERP-2 are bioactive peptides processed from VGF and involved in the control of body fluid homeostasis by regulating vasopressin release. Administration of NERPs suppresses hypertonic saline- or angiotensin II-induced vasopressin release from the hypothalamus and pituitary [ ].
Short Name  VGF

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1 Ontology Annotations

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