Protein Domain : Hypoxia-inducible lipid droplet-associated protein IPR026190

Type  Family
Description  Hypoxia-inducible lipid droplet-associated protein (HILPDA), also known as hypoxia-inducible protein 2 (HIG2), increases intracellular lipid accumulation. It stimulates expression of cytokines including IL6, MIF and VEGFA. It also enhances cell growth and proliferation [ , ]. Human HILPDA is highly expressed in renal cell carcinoma cells but barely detectable in adjacent normal kidney tissue. It is detected in some cervical and endometrial cancers [, , ].
Short Name  Hipoxia_HILPDA

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0 Gene Families

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3 Ontology Annotations

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