Protein Domain : Glioma pathogenesis-related protein 1-like, SCP domain IPR034121

Type  Domain
Description  This SCP-like extracellular protein domain is found in the glioma pathogenesis-related protein (GLIPR) subfamily, which consists of GLIPR1, GLIPR1-like 1 (GLIPR1L1), and GLIPR1-like 2 (GLIPR1L2). GLIPR1 and GLIPR1L2 are expressed in several tissues, whereas GLIPR1L1 is expressed predominantly in the testis and is involved in the binding of sperm to the oocyte complex [ , ].The SCP domain is also known as CAP domain [ ]. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a C-terminal cysteine rich domain, and allergen 5 from vespid venom. It has been proposed that SCP domains may function as endopeptidases.
Short Name  SCP_GLIPR-1-like

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