Protein Domain : Chromobox protein homologue 3, chromo domain IPR038033

Type  Domain
Description  Chromobox protein homologue 3 (CBX3, also known as HP1 gamma) is a component of heterochromatin that binds histone H3 tails methylated at 'Lys-9' which leads to epigenetic repression [ ]. By interacting with MIS12 complex, it is involved in the formation of a functional kinetochore []. It recruits NIPBL to sites of DNA damage at double-strand breaks []. It is a component of the E2F6.com-1 [] and PER [] complexes. The PER complex controls the circadian clock [].This entry represents the CHRomatin Organization Modifier (chromo) domain of CBX3.
Short Name  CBX3_chromo_domain

0 Child Features

0 Gene Families

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0 Ontology Annotations

1 Parent Features

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