Protein Domain : Seminal vesicle protein I IPR002098

Type	Repeat
Description	Seminal vesicle protein I (SVP-1) is one of the four major secretory proteins secreted by Cavia porcellus (Guinea pig) seminal vesicle epithelium. It is a clotting protein that serves as the substrate in the formation of the copulatory plug. Covalent clotting of this protein is catalyzed by a transglutaminase and involves the formation of gamma-glutamyl-epsilon-lysine crosslinks. SVP-1 sequence contains eight repeats of a twenty four amino acid residue domain. There are seven invariant residues in these repeats, three of them (two lysines and one glutamine) probably participate in the cross-links [ ].These repeats are also present twice in the N-terminal region of the precursor of human skin elafin, an inhibitor of elastase as well as in the precursor of Sus scrofa (Pig) sodium/potassium atpase inhibitor SPAI-2.
Short Name	SVP_I