LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | Murine neutrophil gelatinase-associated lipocalin precursor (NGAL) exhibits a 7-10-fold increase in expression in cultured mouse kidney cells infectedby Simian virus 40 (SV40) or other viruses [ ]. NGAL has been identified as a major secretory product of lipopolysaccharide-stimulated cultured mouse macrophages, suggesting that the protein might function in defence againstinfection [ ]. Recently, NGAL has been shown to be identical to SIP24, a previously identified secretory product of quiescent mouse fibroblasts induced by serum, dexamethasone, basic fibroblast growth factor, and phorbolester [ ]. Mouse plasma levels of NGAL rise as a result of increased expression levels in the liver, in response to intramuscular turpentine injection. Tumour necrosis factor can regulate NGAL expression in cultured liver cells. These findings indicate that NGAL is a positive acute phase protein and may possess immunosuppressive or anti-inflammatory properties, possibly linked to its regulation of neutrophil gelatinase or other plasmaprotein [ ]. The uterus is also a major site of NGAL synthesis, especiallyat parturition, when expression increases significantly, suggesting a physiological role for the protein in uterine secretions []. |
| Short Name | LCN2/LCN12 |
