Protein Domain : Immunity protein 63 IPR028952

Type	Domain
Description	Polymorphic toxins systems consist of secreted toxins, primarily involved in intra-specific conflict between related strains of prokaryotes. These toxins are as a rule multi-domain and tend to vary their toxin domains through a process of recombination that might replace an existing toxin domain by a distinct one encoded by standalone cassettes, therefore their name as polymorphic toxins. A key feature that distinguishes the polymorphic toxins from conventional toxins (whose primary targets are in distantly related organisms) is the presence of immunity proteins.This entry represents a predicted immunity protein with an alpha+beta fold and a conserved E+G and ExxY motifs. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbour of the toxin gene, which usually contains toxin domains of the Ntox40, Tox-CdiAC and Tox-ARC families [ ]. The protein is also found in polyimmunity loci in polymorphic toxin systems.
Short Name	Imm63